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Xenical medication is used with a reduced-calorie diet to help significantly overweight persons lose weight. It also helps to prevent regaining weight previously lost. Orlistat works by blocking some of the fat normally digested by the intestine. Fatty/oily stool, oily spotting, intestinal gas with discharge, bowel movement urgency, poor bowel control, or headaches may occur. If these effects persist or worsen, notify your doctor promptly. Intestinal side effects (e.g., oily stool) may increase in intensity if you exceed your daily dietary fat allowance. Tell your doctor immediately if you have any of these unlikely but serious side effects: swelling of the feet or ankles. If you notice other effects not listed above, contact your doctor or pharmacist. Tell your doctor your medical history, including: allergies, digestive disorders (malabsorption or cholestasis), low thyroid function (hypothyroidism), other metabolism problems (e.g., oxalate kidney stones, hyperoxaluria). Xenical should not be used if you have anorexia nervosa or bulemia-type eating disorders. Tell your doctor if you are pregnant before using Xenical. The manufacturer does not recommend use of Xenical during pregnancy. It is not known whether Xenical is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using Xenical is not recommended. Consult your doctor before breast-feeding. Tell your doctor of all nonprescription and prescription medication you may use, especially other weight reducing agents (e.g., diethylpropion), drugs that can raise blood pressure such as decongestants (e.g., pseudoephedrine, phenylpropanolamine), cough suppressants (e.g., dextromethorphan), antidepressants (e.g., nefazodone, fluoxetine, paroxetine, sertraline, fluvoxamine, venlafaxine), lithium, psychiatric medications (e.g., MAO Inhibitors such as selegiline, moclobemide, furazolidone, phenelzine, tranylcypromine), drugs for migraines (e.g., dihydroergotamine, sumatriptan), tryptophan, certain narcotic pain relievers (e.g., meperidine, pentazocine, fentanyl), ketoconazole, erythromycin, high blood pressure medicine or any drugs which can cause drowsiness, including certain antihistamines (e.g., diphenhydramine), sedatives and anti-seizure drugs. Antihistamines and decongestants may be found in many nonprescription drugs for cough and cold. Consult your pharmacist. MAO Inhibitors (see above) and this drug should not be taken together. If an MAO Inhibitor or this drug is stopped, wait 2 weeks before starting the other drug. If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

 

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